TIGIT antibody (C-Term)
-
- Target See all TIGIT Antibodies
- TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
-
Binding Specificity
- C-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TIGIT antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- ALRIHSVEGD LRRKSAGQEE WSPSAPSPPG SCVQAEAAPA GLCGEQRGED
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TIGIT. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human TIGIT
- Top Product
- Discover our top product TIGIT Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 244 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
- Alternative Name
- TIGIT (TIGIT Products)
- Synonyms
- VSIG9 antibody, VSTM3 antibody, WUCAM antibody, ENSMUSG00000071552 antibody, Vstm3 antibody, RGD1563191 antibody, T-cell immunoreceptor with Ig and ITIM domains antibody, T cell immunoreceptor with Ig and ITIM domains antibody, TIGIT antibody, Tigit antibody
- Background
-
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Alias Symbols: DKFZp667A205, FLJ39873, VSIG9, VSTM3, WUCAM
Protein Interaction Partner: PVRL4, PVRL3, PVRL2, PVR,
Protein Size: 244 - Molecular Weight
- 26 kDa
- Gene ID
- 201633
- NCBI Accession
- NM_173799, NP_776160
- UniProt
- Q495A1
- Pathways
- Cancer Immune Checkpoints
-