MNAT1 antibody (N-Term)
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- Target See all MNAT1 Antibodies
- MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MNAT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DDQGCPRCKT TKYRNPSLKL MVNVCGHTLC ESCVDLLFVR GAGNCPECGT
- Cross-Reactivity
- Cow (Bovine), Dog (Canine), Chicken, Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MNAT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MNAT1
- Top Product
- Discover our top product MNAT1 Primary Antibody
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- Application Notes
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WB Suggested Anti-MNAT1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 309 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))
- Alternative Name
- MNAT1 / RNF66 (MNAT1 Products)
- Synonyms
- F6I18.270 antibody, F6I18_270 antibody, Afu4g08900 antibody, E130115E11Rik antibody, MAT1 antibody, P36 antibody, zgc:101599 antibody, CAP35 antibody, RNF66 antibody, TFB3 antibody, cyclin-dependent kinase-activating kinase assembly factor-related / CDK-activating kinase assembly factor-like protein antibody, CDK-activating kinase assembly factor MAT1 antibody, MNAT1, CDK activating kinase assembly factor antibody, menage a trois 1 antibody, MNAT CDK-activating kinase assembly factor 1 antibody, MNAT1, CDK activating kinase assembly factor L homeolog antibody, AT4G30820 antibody, AFUA_4G08900 antibody, NFIA_107260 antibody, CpipJ_CPIJ001565 antibody, AFLA_110530 antibody, BDBG_00548 antibody, TERG_06789 antibody, Tsp_08309 antibody, mnat1 antibody, Mnat1 antibody, MNAT1 antibody, mnat1.L antibody
- Background
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The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH, MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-498 AA053721.1 1-498 499-1372 BC000820.1 489-1362 1373-1388 BU620200.1 1-16 c
Alias Symbols: MAT1, RNF66, TFB3, CAP35
Protein Interaction Partner: RPA3, RPA2, RPA1, CDK7, CDK2, MBP, CTD, CCNH, NGFRAP1, UBC, NKX3-1, USP2, SUPT5H, POLR2A, GTF2H4, GTF2H3, GTF2H1, ERCC2, tat, TRIM39, TRIM34, TRIM17, TRIM2, ICK, TRIM31, RNF41, RNF7, TRIM26, MKRN3, TRIM21, MDM4, BRCA1, TRIML1, RNF32, TRIM9, TRIM5, XBP1P1,
Protein Size: 309 - Molecular Weight
- 36 kDa
- Gene ID
- 4331
- NCBI Accession
- NM_002431, NP_002422
- UniProt
- P51948
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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