SGK1 antibody (AbBy Fluor® 594)
-
- Target See all SGK1 Antibodies
- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
-
Reactivity
- Human, Mouse, Rat, Cow, Dog
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SGK1 antibody is conjugated to AbBy Fluor® 594
-
Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Cow, Dog, Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SGK1
- Isotype
- IgG
- Top Product
- Discover our top product SGK1 Primary Antibody
-
-
- Application Notes
- IF(IHC-P)(1:50-200)
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
- Alternative Name
- SGK1 (SGK1 Products)
- Synonyms
- SGK antibody, Sgk antibody, sgk-B antibody, sgk2 antibody, cb1083 antibody, sgk antibody, wu:fc20a09 antibody, sgk-A antibody, sgk1 antibody, sgk1-a antibody, sgk1-b antibody, serum/glucocorticoid regulated kinase 1 antibody, Serine/threonine-protein kinase sgk-1 antibody, serum/glucocorticoid regulated kinase 1 S homeolog antibody, serum/glucocorticoid regulated kinase 1 L homeolog antibody, SGK1 antibody, Sgk1 antibody, sgk-1 antibody, sgk1.S antibody, sgk1 antibody, sgk1.L antibody
- Background
-
Synonyms: Serum/glucocorticoid regulated kinase 1, SGK 1, SGK-1, Serine/threonine protein kinase SGK, Serine/threonine protein kinase Sgk1, Serum and glucocorticoid regulated kinase, Serum/glucocorticoid regulated kinase, SGK 1, SGK.
Background: SGK1 is a protein kinase that plays an important role in cellular stress response. SGK1 activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels of SGK1 and activity may contribute to conditions such as hypertension and diabetic nephropathy. This protein also mediates cell survival signals, as it has been shown to phosphorylate and negatively regulate the pro apoptotic FOXO3A protein. Ser 422 is a critical site on the protein and may be involved in its activation.
- Pathways
- MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
-