Tryptophan Hydroxylase 2 antibody
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- Target See all Tryptophan Hydroxylase 2 (TPH2) Antibodies
- Tryptophan Hydroxylase 2 (TPH2)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Tryptophan Hydroxylase 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio)
- Characteristics
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Rabbit Polyclonal antibody to TPH2 (tryptophan hydroxylase 2)
TPH2 antibody [N3C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human TPH2. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product TPH2 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: mouse hippocampus , mouse midbrain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.3 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Tryptophan Hydroxylase 2 (TPH2)
- Alternative Name
- tryptophan hydroxylase 2 (TPH2 Products)
- Synonyms
- ADHD7 antibody, NTPH antibody, Ntph antibody, tphR antibody, wu:fq15a04 antibody, AU043594 antibody, tryptophan hydroxylase 2 antibody, tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) antibody, TPH2 antibody, Tph2 antibody, tph2 antibody
- Background
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This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
- Molecular Weight
- 56 kDa
- Gene ID
- 121278
- UniProt
- Q8IWU9
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