Endoglin antibody

Catalog No. ABIN285707

Product Details anti-Endoglin Antibody

Target: Endoglin (ENG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

Purification: Protein A affinity chromatography

Immunogen: CD105 antibody was raised in rabbit using recombinant human soluble CD105/Endoglin as the immunogen.

Isotype: IgG

Application Details

Application Notes: ELISA: 1-15 µg/mL, FC: 3-20 µg/mL, IHC: 6-30 µg/mL, WB: 1-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH7.4 with out of preservative.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105 (ENG Products)

Synonyms: ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody

Background: Endoglin, also known as CD105, is a Type I integral membrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated, cytoplasmic tail. Two splice variants of human endoglin, the S endoglin and L-endoglin that differ in the length of their cytoplasmic tails have been identified. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta.