BCR antibody (Biotin)

Catalog No. ABIN289944

Product Details anti-BCR Antibody (Biotin)

Target: BCR (Breakpoint Cluster Region (BCR))

Reactivity: All Species

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCR antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (IHC)

Purification: The splenic lymphocytes from BALB/c mouse, immunized with CML-KLH were fused to myeloma P3U1 cells. The cell line (CMS-10) with positive reaction wasgrown in ascitic fluid of BALB/c mouse, from which the antibody was purified byProtein G affinity chromatography and conjugated.

Immunogen: CML-KLH

Clone: CMS-10

Isotype: IgG1

Application Details

Application Notes: Working dilution for immunohistochemistry: 5-10ug/ml, for ELISA: 0.1-1.0ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for BCR

Target: BCR (Breakpoint Cluster Region (BCR))

Alternative Name: CML (BCR Products)

Synonyms: si:dkey-83d9.7 antibody, zK83D9.7 antibody, BCR antibody, ALL antibody, BCR1 antibody, CML antibody, D22S11 antibody, D22S662 antibody, PHL antibody, 5133400C09Rik antibody, AI561783 antibody, AI853148 antibody, mKIAA3017 antibody, breakpoint cluster region antibody, BCR, RhoGEF and GTPase activating protein antibody, bcr antibody, BCR antibody, Bcr antibody

Background: Reaction of protein amino groups with glucose leads, through the early products such as a Schiff baseand Amadori rearrangement products, to the formation of advanced glycation end products (AGEs). Recent immunological studies using anti-AGEs antibody (6D12) demonstrated the presence of AGEs-modifiedproteins in several human tissues: human lens (nondiabetic and noncataractous), renal proximaltubules in patients with diabetic nephropathy and chronic renal failure, diabetic retina, peripheral nerves of diabetic neuropathy, atherosclerotic lesions of arterial walls, beta2-microglobulin forming amyloid fibrils in patients with hemodialysis-related amyloidosis, senileplaques of patients with Alzheimer

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling