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Integrin Alpha2b antibody (APC)

CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 APC
Catalog No. ABIN303530
  • Target See all Integrin Alpha2b (CD41) Antibodies
    Integrin Alpha2b (CD41)
    Reactivity
    • 108
    • 29
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    • 5
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    Human
    Host
    • 67
    • 43
    • 20
    Mouse
    Clonality
    • 84
    • 40
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    Monoclonal
    Conjugate
    • 55
    • 14
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    • 1
    • 1
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    This Integrin Alpha2b antibody is conjugated to APC
    Application
    • 94
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    Flow Cytometry (FACS)
    Purification
    Size-Exclusion Chromatography.
    Immunogen
    Leukocytes of patient suffering from LGL-type leukaemia
    Clone
    MEM-06
    Isotype
    IgG1
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  • Application Notes
    Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as a stabilizing agent.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.
    Expiry Date
    12 months
  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    CD41 / ITGA2B (CD41 Products)
    Synonyms
    AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
    Background
    CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
    UniProt
    P08514
    Pathways
    Integrin Complex
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