TRAF3 antibody (Middle Region)

Catalog No. ABIN3042952

Product Details anti-TRAF3 Antibody

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Binding Specificity: AA 387-403, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for TNF receptor-associated factor 3(TRAF3) detection. Tested with WB in Human,Mouse,Rat.

Sequence: RHDQMLSVHD IRLADMD

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for TNF receptor-associated factor 3(TRAF3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: TNF receptor-associated factor 3
Protein Name: TNF receptor-associated factor 3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TRAF3(387-403aa RHDQMLSVHDIRLADMD), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for TRAF3 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRAF3

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Alternative Name: TRAF3 (TRAF3 Products)

Synonyms: CAP-1 antibody, CAP1 antibody, CD40bp antibody, CRAF1 antibody, IIAE5 antibody, LAP1 antibody, AI528849 antibody, T-BAM antibody, amn antibody, TNF receptor associated factor 3 antibody, TNF receptor-associated factor 3 antibody, Tnf receptor-associated factor 3 antibody, TRAF3 antibody, Traf3 antibody

Background: TRAF3(TNF Receptor-Associated Factor 3), also called LAP1, CAP1, CRAF1 or CD40BP, is a protein that in humans is encoded by the TRAF3 gene. The protein encoded by this gene is a member of the TNF receptor(TNFR) associated factor(TRAF) protein family. Gross(2012) mapped the TRAF3 gene to chromosome 14q32.32 based on an alignment of the TRAF3 sequence with the genomic sequence(GRCh37). Dadgostar et al.(2003) determined that the coiled-coil domain of mouse T3jam interacted with the isoleucine zipper domain of Traf3. Oganesyan et al.(2006) demonstrated that cells lacking TRAF3 are defective in type I interferon responses activated by several different Toll-like receptors.

Synonyms: CAP 1 antibody|CAP-1 antibody|CAP1 antibody|CD40 associated protein 1 antibody|CD40 binding protein antibody|CD40 bp antibody|CD40 receptor associated factor 1 antibody|CD40 receptor-associated factor 1 antibody|CD40-binding protein antibody|CD40bp antibody|CRAF 1 antibody|CRAF1 antibody|IIAE5 antibody|LAP 1 antibody|LAP1 antibody|LMP1 associated protein antibody|LMP1-associated protein 1 antibody|MIPT3 antibody|TNF receptor associated factor 3 antibody|TNF receptor-associated factor 3 antibody|TRAF 3 antibody|Traf3 antibody|TRAF3_HUMAN antibody

UniProt: Q13114

Pathways: NF-kappaB Signaling, Apoptosis, TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades