RNASE1 antibody (Middle Region)

Catalog No. ABIN3043179

Product Details anti-RNASE1 Antibody

Target: RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))

Binding Specificity: AA 72-90, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASE1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Ribonuclease pancreatic(RNASE1) detection. Tested with WB in Human.

Sequence: NTFVHEPLVD VQNVCFQEK

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Ribonuclease pancreatic(RNASE1) detection. Tested with WB in Human.
Gene Name: ribonuclease, RNase A family, 1(pancreatic)
Protein Name: Ribonuclease pancreatic

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Ribonuclease A(72-90aa NTFVHEPLVDVQNVCFQEK).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RNASE1

Target: RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))

Alternative Name: RNASE1 (RNASE1 Products)

Synonyms: RNASE1 antibody, RNS1 antibody, ATRNS1 antibody, RIBONUCLEASE 1 antibody, T17M13.16 antibody, T17M13_16 antibody, ribonuclease 1 antibody, RIB1 antibody, AI574248 antibody, Rib-1 antibody, Rib1 antibody, SRN antibody, ribonuclease A family member 1, pancreatic antibody, ribonuclease pancreatic-like antibody, ribonuclease A family member k6 antibody, Ribonuclease 1 antibody, ribonuclease 1 antibody, ribonuclease, RNase A family, 1 (pancreatic) antibody, ribonuclease pancreatic antibody, RNASE1 antibody, LOC475395 antibody, RNASE6 antibody, Rnase1 antibody, RNS1 antibody, LOC101113761 antibody

Background: RIBONUCLEASE A FAMILY, 1(Ribonuclease pancreatic) is an enzyme that in humans is encoded by the RNASE1 gene. By genomic sequence analysis, RNASE1 gene is mapped the to chromosome 14q11.2, where it is linked to 7 other RNase A superfamily genes. Monomeric human pancreatic RNase, devoid of any biological activity other than its RNA degrading ability, was engineered into a dimeric protein with a cytotoxic action on mouse and human tumor cells, but lacking any appreciable toxicity on mouse and human normal cells. This dimeric variant of human pancreas RNase selectively sensitizes to apoptotic death cells derived from a human thyroid tumor. Because of its selectivity for tumor cells, and because of its human origin, this protein represents a potentially very attractive, novel tool for anticancer therapy.

Synonyms: HP-RNase antibody|Pancreatic ribonuclease antibody|Rib 1 antibody|RIB-1 antibody|Rib1 antibody|Ribonuclease 1 antibody|Ribonuclease A antibody|Ribonuclease a family 1 antibody|Ribonuclease pancreatic antibody|Ribonuclease RNase A family 1 antibody|Ribonuclease RNase A family 1 pancreatic antibody|RNAS1_HUMAN antibody|RNase 1 antibody|RNAse A antibody|RNase UpI-1 antibody|Rnase1 antibody|RNAseA antibody

UniProt: P07998