SPI1 antibody (AA 124-271)
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- Target See all SPI1 Antibodies
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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Binding Specificity
- AA 124-271
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SPI1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human SPI1 (AA: 124-271) expressed in E. coli., ,
- Clone
- 5C7
- Isotype
- IgG1
- Top Product
- Discover our top product SPI1 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60." in: Leukemia research, Vol. 34, Issue 12, pp. 1636-46, (2010) (PubMed).
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PU.1 can regulate the ZNF300 promoter in APL-derived promyelocytes HL-60." in: Leukemia research, Vol. 34, Issue 12, pp. 1636-46, (2010) (PubMed).
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- Target
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
- Alternative Name
- SPI1 (SPI1 Products)
- Synonyms
- OF antibody, PU.1 antibody, SFPI1 antibody, SPI-1 antibody, SPI-A antibody, Dis-1 antibody, Dis1 antibody, Sfpi-1 antibody, Sfpi1 antibody, Spi-1 antibody, Tcfpu1 antibody, Tfpu.1 antibody, Pu.1 antibody, cb1086 antibody, pu.1 antibody, pu1 antibody, sfpi1 antibody, si:by184l24.2 antibody, spi1 antibody, SPI1/PU.1 antibody, spi1l antibody, zgc:152991 antibody, Spi-1 proto-oncogene antibody, spleen focus forming virus (SFFV) proviral integration oncogene antibody, Spi-1 proto-oncogene b antibody, Spi-1 proto-oncogene a antibody, SPI1 antibody, Spi1 antibody, spi1b antibody, spi1a antibody
- Background
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Description: This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: OF, PU.1, SFPI1, SPI-1, SPI-A
- Molecular Weight
- 42 kDa
- Gene ID
- 6688
- HGNC
- 6688
- Pathways
- Stem Cell Maintenance
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