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Tyrosine Hydroxylase antibody

TH Reactivity: Human, Rat, Mouse, Protozoa WB, IHC, IF, ICC Host: Sheep Polyclonal unconjugated
Catalog No. ABIN308677
  • Target See all Tyrosine Hydroxylase (TH) Antibodies
    Tyrosine Hydroxylase (TH)
    Reactivity
    • 111
    • 101
    • 93
    • 11
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Protozoa
    Host
    • 106
    • 22
    • 6
    • 4
    • 2
    Sheep
    Clonality
    • 109
    • 31
    Polyclonal
    Conjugate
    • 89
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Tyrosine Hydroxylase antibody is un-conjugated
    Application
    • 96
    • 66
    • 35
    • 20
    • 18
    • 18
    • 16
    • 15
    • 14
    • 13
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse (Murine), Primate, Rat (Rattus)
    Purification
    affinity purified
    Immunogen
    Native rat tyrosine hydroxylase purified from pheochromocytoma.
    Isotype
    IgG
    Top Product
    Discover our top product TH Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    -20 °C
  • Target
    Tyrosine Hydroxylase (TH)
    Alternative Name
    Tyrosine Hydroxylase (TH Products)
    Synonyms
    DYT14 antibody, DYT5b antibody, TYH antibody, The antibody, CG10118 antibody, DH65B antibody, DTH antibody, Dmel\\CG10118 antibody, Pale antibody, Ple antibody, TH antibody, Th antibody, VII antibody, dTH1 antibody, dTH65B antibody, pale/ple antibody, th antibody, dyt14 antibody, dyt5b antibody, tyh antibody, tyrosine hydroxylase antibody, pale antibody, tyrosine 3-monooxygenase antibody, tyrosine hydroxylase S homeolog antibody, TH antibody, Th antibody, ple antibody, th antibody, th.S antibody, LOC100008895 antibody
    Background
    Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. TH has a large molecular diversity, resulting from differential splicing of its mRNA, which is tissue specific and might result in long term changes in activity of the enzyme and the availability of neurotransmitter at various synapses. The presence of different DNA sequences at the TH locus confers susceptibility to various disorders of the brain including manic-depression and schizophrenia. Parkinson's disease is also considered a TH deficiency, as low dopamine levels are a consistent neurochemical abnormality.
    Pathways
    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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