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Amino-terminal Enhancer of Split (AES) (C-Term) antibody

Details for Product No. ABIN309826
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Antigen
Synonyms grg, esp1, grg5, tle5, aes-1, aes-2, AES, GRG, ESP1, GRG5, TLE5, AES-1, AES-2, AL024115, Esp1, Grg, Grg-5, Grg5, Tle5, zgc:64216, xgrg-5
Epitope
C-Term
(23), (15), (7), (2), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
(55), (28), (15), (1), (1), (1)
Host
Rabbit
(51), (5), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(53), (27), (22), (10), (7), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN309826
229.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the C terminal of human AES
Sequence GLQPPSLPAVSAGTGLLSLSALGSQAHLSKEDKNGHDGDT HQEDDGEKSD
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against AES. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name AES
Background AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genesThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 22 kDa
Gene ID 166
NCBI Accession NM_001130, NP_001121
UniProt Q08117
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 197 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Amino-terminal Enhancer of Split (AES) (C-Term) antibody WB Suggested Anti-AES Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate
Background publications Jan, Matter, Pai et al.: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, 2004 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN309826
229.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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