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THO Complex 4 (THOC4) (N-Term) antibody

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Antigen
Epitope
N-Term
(18), (16), (11), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(54), (16), (11), (4), (2), (1), (1), (1)
Host
Rabbit
(45), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(49), (33), (13), (11), (8), (8), (6), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human THOC4
Sequence GGGPIRNRPA IARGAAGGGG RNRPAPYSRP KQLPDKWQHD LFDSGFGGGA
Predicted Reactivity Bovine : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against THOC4. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name THOC4 (THOC4 Antibody Abstract)
Background THOC4 is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.
Molecular Weight 28 kDa
Gene ID 10189
NCBI Accession NM_005782, NP_005773
UniProt Q86V81
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 257 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-THO Complex 4 (THOC4) (N-Term) antibody (ABIN310422) WB Suggested Anti-THOC4 Antibody Titration: 2.5ug/ml
Positive Control: <...
Product cited in: Ding, Enriquez-Algeciras, Dave et al.: "The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis." in: EMBO reports, Vol. 13, Issue 3, pp. 230-6, 2012 (PubMed).

Strässer, Masuda, Mason et al.: "TREX is a conserved complex coupling transcription with messenger RNA export." in: Nature, Vol. 417, Issue 6886, pp. 304-8, 2002 (PubMed).

Catalog No. ABIN310422

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