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Details for Product No. ABIN310641

LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (N-Term) antibody

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Antigen
Synonyms SCDO3, AW061165
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN310641
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-LFNG antibody: synthetic peptide directed towards the N terminal of human LFNG
Sequence LSEYFSLLTRARRDAGPPPGAAPRPADGHPRPLAEPLAPR DVFIAVKTTK
Predicted Reactivity Human : 100%, Mouse : 100%, Rat : 100%, Bovine : 92%, Rabbit : 84%
Characteristics This is a rabbit polyclonal antibody against LFNG. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name LFNG
Background LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.
Molecular Weight 39kDa
Gene ID 3955
NCBI Accession NP_001035258, NM_001040168
UniProt Q8NES3-3
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-LFNG antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Sparrow, Chapman, Wouters et al.: "Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype." in: American journal of human genetics, Vol. 78, Issue 1, pp. 28-37, 2005 (PubMed).

Alternatives for antigen "LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG)", type "Antibodies"
Hosts (17), (13)
Reactivities (29), (7), (7)
Applications (23), (22), (3), (3), (3), (2), (2), (1)
Epitopes (10), (4), (2), (2), (2), (1), (1), (1)
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