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LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (N-Term) antibody

Details for Product No. ABIN310641
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Antigen
Synonyms SCDO3, AW061165
Epitope
N-Term
(9), (8), (5), (4), (3), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(43), (8), (8)
Host
Rabbit
(22), (22)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (1)
Application
Western Blotting (WB)
(37), (32), (9), (8), (5), (3), (3), (2), (2)
Pubmed 1 reference available
Quantity 50 µg
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN310641
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human LFNG
Sequence LSEYFSLLTRARRDAGPPPGAAPRPADGHPRPLAEPLAPR DVFIAVKTTK
Predicted Reactivity Human : 100 %, Mouse : 100 %, Rat : 100 %, Bovine : 90 %, Rabbit : 80 %
Characteristics This is a rabbit polyclonal antibody against LFNG. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name LFNG
Background LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.
Molecular Weight 39 kDa
Gene ID 3955
NCBI Accession NM_001040168, NP_001035258
UniProt Q8NES3-3
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 361 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (N-Term) antibody WB Suggested Anti-LFNG Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Muscle
Background publications Sparrow, Chapman, Wouters et al.: "Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype." in: American journal of human genetics, Vol. 78, Issue 1, pp. 28-37, 2005 (PubMed).

Hosts (22), (22)
Reactivities (43), (8), (8)
Applications (37), (32), (9), (8), (5), (3), (3), (2), (2)
Conjugates (2), (2), (2), (2), (2), (1)
Epitopes (9), (8), (5), (4), (3), (2), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN310641
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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