CD36 Molecule (thrombospondin Receptor) (CD36) (N-Term) antibody

Details for Product No. ABIN310976
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Antigen
Synonyms
CPH, Cph-1, Cph1, R74677, fat, FAT, GPIV, Scarb3, BDPLT10, CHDS7, GP3B, GP4, PASIV, SCARB3, Fat, GPIIIB, PAS-4, Fath, FAT1, AI120173, CD36, Cd36l1, Cla-1, Cla1, D5Ertd460e, Hdlq1, Hlb398, SR-B1, SR-BI ... show more
CPH, Cph-1, Cph1, R74677, fat, FAT, GPIV, Scarb3, BDPLT10, CHDS7, GP3B, GP4, PASIV, SCARB3, Fat, GPIIIB, PAS-4, Fath, FAT1, AI120173, CD36, Cd36l1, Cla-1, Cla1, D5Ertd460e, Hdlq1, Hlb398, SR-B1, SR-BI, SRBI, Srb1, mSR-BI show less
Epitope
N-Term
(13), (9), (7), (6), (4), (4), (3), (2), (1), (1), (1), (1)
Reactivity
Rabbit, Rat (Rattus), Dog (Canine), Cow (Bovine), Pig (Porcine), Human
(198), (97), (68), (32), (27), (25), (17), (7), (1), (1)
Host
Rabbit
(131), (96), (26), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(33), (15), (9), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(147), (92), (41), (38), (37), (30), (30), (28), (22), (13), (10), (7), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN310976
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human CD36
Sequence MGCDRNCGLI AGAVIGAVLA VFGGILMPVG DLLIQKTIKK QVVLEEGTIA
Predicted Reactivity Human : 100 %, Bovine : 70 %, Dog : 70 %, Goat : 70 %, Pig : 70 %, Rabbit : 70 %, Rat : 70 %
Characteristics This is a rabbit polyclonal antibody against CD36. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name CD36
Background CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in its gene cause platelet glycoprotein deficiency.The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Molecular Weight 53 kDa
Gene ID 948
NCBI Accession NM_001001547, NP_001001547
UniProt P16671
Research Area Cancer, Atherosclerosis, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 472 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-CD36 Molecule (thrombospondin Receptor) (CD36) (N-Term) antibody anti-CD36 Molecule (thrombospondin Receptor) (CD36) (N-Term) antibody
anti-CD36 Molecule (thrombospondin Receptor) (CD36) (N-Term) antibody (2) anti-CD36 Molecule (thrombospondin Receptor) (CD36) (N-Term) antibody (Image 2)
Background publications Ozer, Negis, Aytan et al.: "Vitamin E inhibits CD36 scavenger receptor expression in hypercholesterolemic rabbits." in: Atherosclerosis, Vol. 184, Issue 1, pp. 15-20, 2005 (PubMed).

Validation Images
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