Cathepsin D antibody (AA 21-412)
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- Target See all Cathepsin D (CTSD) Antibodies
- Cathepsin D (CTSD)
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Binding Specificity
- AA 21-412
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cathepsin D antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- The antibody recognizes Human Cathepsin D. Other species not tested.
- Characteristics
- Synonyms: CTSD, CPSD
- Purification
- Protein-G affinity chromatography
- Immunogen
- Recombinant human Cathepsin D (21-412 aa) purified from E. coli
- Clone
- 4G2
- Isotype
- IgG2b
- Top Product
- Discover our top product CTSD Primary Antibody
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- Application Notes
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ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on paraffin-embedded tissues (1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- Cathepsin D (CTSD)
- Alternative Name
- Cathepsin D (CTSD Products)
- Synonyms
- catD antibody, fb93e11 antibody, fj17b09 antibody, wu:fb93e11 antibody, wu:fj17b09 antibody, LOC398557 antibody, Cathd antibody, CatD antibody, LOC100136761 antibody, CTSD antibody, DKFZp469J0315 antibody, DDBDRAFT_0205785 antibody, DDBDRAFT_0215012 antibody, DDB_0205785 antibody, DDB_0215012 antibody, CLN10 antibody, CPSD antibody, CD antibody, cathepsin D antibody, cathepsin D S homeolog antibody, lysosomal aspartic protease antibody, cathepsin D-like antibody, ctsd antibody, LOC398557 antibody, ctsd.S antibody, CatD antibody, LOC5567565 antibody, LOC100136761 antibody, CTSD antibody, Cathd antibody, ctsD antibody, catd antibody, Ctsd antibody, LOC443060 antibody
- Background
- The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D.Synonyms: CPSD, CTSD
- Gene ID
- 1509
- UniProt
- P07339
- Pathways
- Peptide Hormone Metabolism
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