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STAT2 antibody (Signal Transducer and Activator of Transcription 2, 113kDa) (Tyr690)

Details for Product anti-STAT2 Antibody No. ABIN319410, Supplier: Log in to see
Antigen
Alternatives
anti-Human STAT2 antibody for Western Blotting
Epitope
Tyr690
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42
22
17
15
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13
13
11
9
8
5
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3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
218
80
58
3
3
3
3
3
3
3
3
Host
Rabbit
229
25
1
Clonality
Polyclonal
Conjugate
This STAT2 antibody is un-conjugated
10
9
8
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6
6
3
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
203
92
90
29
24
22
7
4
4
3
3
3
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human STAT2 around the phosphorylation site of Tyrosine 690 (R-K-YP-L-K).
Specificity This antibody detects endogenous levels of total STAT2 protein.
Purification Immunoaffinity Chromatography.
Alternative Name STAT2 (STAT2 Antibody Abstract)
Background Synonyms: Signal transducer and activator of transcription 2, p113
Gene ID 6773
NCBI Accession NP_005410
UniProt P52630
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling
Application Notes Western Blot (1/500-1/1000). Immunohistochemistry (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at-20 °C.
Supplier Images
 image for anti-STAT2 antibody (Signal Transducer and Activator of Transcription 2, 113kDa) (Tyr690) (ABIN319410) anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (Tyr690) antibody
 image for anti-STAT2 antibody (Signal Transducer and Activator of Transcription 2, 113kDa) (Tyr690) (ABIN319410) anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (Tyr690) antibody (Image 2)
Background publications Schamel, Reth: "Monomeric and oligomeric complexes of the B cell antigen receptor." in: Immunity, Vol. 13, Issue 1, pp. 5-14, 2000 (PubMed).

Horvath, Stark, Kerr et al.: "Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex." in: Molecular and cellular biology, Vol. 16, Issue 12, pp. 6957-64, 1997 (PubMed).

Improta, Schindler, Horvath et al.: "Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 11, pp. 4776-80, 1994 (PubMed).

Fu, Schindler, Improta et al.: "The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 16, pp. 7840-3, 1992 (PubMed).