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CD45 antibody (Protein tyrosine Phosphatase, Receptor Type, C)

Details for Product anti-PTPRC Antibody No. ABIN320035, Supplier: Log in to see
Antigen
  • PTPRC
  • si:dkeyp-47c5.1
  • B220
  • CD45
  • CD45R
  • GP180
  • L-CA
  • LCA
  • LY5
  • T200
  • Cd45
  • Ly-5
  • Lyt-4
  • loc
  • Lca
  • RT7
  • cd45
  • protein tyrosine phosphatase, receptor type, C
  • PTPRC
  • ptprc
  • Ptprc
Alternatives
anti-Human CD45 antibody for Immunocytochemistry
Reactivity
Human
1406
732
211
137
69
51
45
44
24
21
19
13
5
5
4
3
3
1
1
1
1
1
1
Host
Mouse
1458
782
233
3
2
Clonality (Clone)
Monoclonal ()
Conjugate
This CD45 antibody is un-conjugated
288
238
177
98
63
60
57
49
45
39
36
34
33
33
33
33
27
26
26
24
21
17
16
14
14
12
12
10
10
10
9
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6
6
6
5
5
5
5
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
2046
534
531
525
464
435
434
359
205
54
40
38
30
28
26
16
11
10
8
7
6
6
4
4
3
2
2
2
2
2
2
2
2
1
1
Options
Supplier
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Immunogen Human T lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Clone F8-11-13
Isotype IgG1
Specificity This antibody recognises the human CD45RA cell surface antigen. Clone F8-11-13 reacts with the high molecular weight form of the leucocyte common antigen (LCA) expressed by B lymphocytes and a subset of T lymphocytes.
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Alternative Name CD45 / LCA (PTPRC Antibody Abstract)
Background CD45 is a complex molecule existing in a number of isoforms. Antibodies recognising a common epitope on all of these isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
Gene ID 5788
NCBI Accession NP_002829
UniProt P08575
Pathways Regulation of Leukocyte Mediated Immunity
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted at -20 °C.
Background publications Franitza, Kollet, Brill, Vaday, Petit, Lapidot, Alon, Lider: "TGF-beta1 enhances SDF-1alpha-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules." in: European journal of immunology, Vol. 32, Issue 1, pp. 193-202, 2001 (PubMed).

OGrady, Stewart, Lowrey, Howie, Krajewski: "CD40 expression in Hodgkin's disease." in: The American journal of pathology, Vol. 144, Issue 1, pp. 21-6, 1994 (PubMed).

Dalchau, Fabre et al.: "Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the ..." in: The Journal of experimental medicine, Vol. 153, Issue 4, pp. 753-65, 1981 (PubMed).