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Details for Product No. ABIN347118

Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody

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Antigen
Synonyms Nyw1, 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, DCAF3, WDR94
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN347118
Quantity 200 µL
Price
573.54 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 5 to 6 Business Days
Immunogen Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
Isotype IgG
Specificity Reacts with mouse 120 kDa Ambra1 protein.
Cross-Reactivity (Details) Reacts with mouse 120 kDa Ambra1 protein. Cross reacts with human and rat protein.
Purification Antiserum
Alternative Name Activating molecule in Beclin 1-regulated autophagy (Ambra-1)
UniProt Q9C0C7
Application Notes Optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1 M, glycine 0,1 M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20 °C. Store reconstituted antibodies at +4 °C. For extended periods store in aliquots at -20 °C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
Product cited in: Di Bartolomeo, Corazzari, Nazio et al.: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, 2010 (PubMed).

Armstrong, Corazzari, Martin et al.: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, 2011 (PubMed).

Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

Alternatives for antigen "Autophagy/beclin-1 Regulator 1 (AMBRA1)", type "Antibodies"
Hosts (58)
Reactivities (50), (44), (30), (14), (12), (2)
Applications (48), (30), (23), (17), (10), (6), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (9), (3), (2), (1)
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