You are viewing an incomplete version of our website. Please click to reload the website as full version.

Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody

Details for Product No. ABIN347118, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Epitope
N-Term
Reactivity
Human, Mouse (Murine), Rat (Rattus)
Host
Rabbit
Clonality
Polyclonal
Application
ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 3 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 200 μL
Options
Shipping to United States ( )
Availability Will be delivered in 5 to 6 Business Days
Immunogen Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
Isotype IgG
Specificity Reacts with mouse 120 kDa Ambra1 protein. Cross reacts with human and rat protein.
Cross-Reactivity (Details) Reacts with mouse 120 kDa Ambra1 protein. Cross reacts with human and rat protein.
Purification Antiserum
Background Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation
UniProt Q9C0C7
Application Notes Optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Storage -20 °C,4 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
Supplier Images
Image no. 1 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347118) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody
Image no. 2 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347118) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (Image 2)
Image no. 3 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347118) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (Image 3)
Image no. 4 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347118) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (Image 4)
Image no. 5 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347118) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (Image 5)
Image no. 6 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347118) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (Image 6)
Image no. 7 for anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (ABIN347118) anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody (Image 7)
Product cited in: Armstrong, Corazzari, Martin et al.: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, 2011 (PubMed).

Di Bartolomeo, Corazzari, Nazio et al.: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, 2010 (PubMed).

Background publications Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

Catalog No. ABIN347118
$464.80
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)