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RENT1/UPF1 antibody (N-Term)
UPF1
Reactivity: Human, Mouse
EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RENT1/UPF1 Antibody
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Target
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RENT1/UPF1 (UPF1)
(UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
Binding Specificity
All epitopes for RENT1/UPF1 antibodies
N-Term
Reactivity
All reactivities for RENT1/UPF1 antibodies
Human, Mouse
Host
All hosts for RENT1/UPF1 antibodies
Rabbit
Clonality
All clonalities for RENT1/UPF1 antibodies
Polyclonal
Conjugate
All conjugates for RENT1/UPF1 antibodies
This RENT1/UPF1 antibody is un-conjugated
Application
All applications for RENT1/UPF1 antibodies
Enzyme Immunoassay (EIA)
Specificity
This antibody detects RENT1 at N-term.
Purification
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RENT1.
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
ELISA 1: 1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target Details for RENT1/UPF1
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Target
RENT1/UPF1 (UPF1)
(UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
Alternative Name
UPF1 / RENT1 (UPF1 Products )
Synonyms
HUPF1 antibody, NORF1 antibody, RENT1 antibody, pNORF1 antibody, smg-2 antibody, B430202H16Rik antibody, PNORF-1 antibody, Rent1 antibody, Upflp antibody, rent1 antibody, wu:fi40f07 antibody, wu:fj48a01 antibody, zgc:55472 antibody, Tb05.3C6.50 antibody, AO090012000584 antibody, hupf1 antibody, norf1 antibody, pnorf1 antibody, upf1 antibody, UPF1, RNA helicase and ATPase antibody, UPF1 regulator of nonsense transcripts homolog (yeast) antibody, upf1 regulator of nonsense transcripts homolog (yeast) antibody, regulator of nonsense transcripts 1 antibody, Regulator of nonsense transcripts 1 antibody, UPF1 regulator of nonsense transcripts homolog S homeolog antibody, UPF1 antibody, Upf1 antibody, upf1 antibody, Tc00.1047053511317.30 antibody, Tb927.5.2140 antibody, TVAG_453890 antibody, TVAG_237840 antibody, AOR_1_1018194 antibody, HPB8_739 antibody, smg-2 antibody, upf1.S antibody
Background
RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.Synonyms: ATP-dependent helicase RENT1, KIAA0221, NORF1, Nonsense mRNA reducing factor 1, Regulator of nonsense transcripts 1, Up-frameshift suppressor 1 homolog
Molecular Weight
124345 Da
Gene ID
5976, 9606
UniProt
Q92900
Pathways
SARS-CoV-2 Protein Interactome
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