anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (pTyr996)

Details for Product anti-KDR Antibody No. ABIN358131
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Antigen
Synonyms
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f ... show more
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f21.4, wu:fc31a09, fk52c05, flk, kdr, kdra, vegfr2, vegfr4, vegr2, wu:fk52c05 show less
Epitope
pTyr996
(87), (49), (47), (46), (31), (26), (24), (21), (20), (19), (16), (13), (13), (11), (11), (11), (9), (8), (7), (7), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(582), (320), (199), (7), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Host
Rabbit
(537), (92), (41), (3), (3), (2), (1)
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
(40), (21), (20), (16), (14), (12), (6), (6), (6), (6), (6), (6), (6), (6), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(463), (245), (220), (124), (119), (111), (50), (40), (32), (21), (18), (15), (14), (7), (6), (4), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
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Availability Will be delivered in 6 to 8 Business Days
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Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y996 of human KDR/FLK1
Isotype Ig
Specificity This antibody detects CD309 (KDR/Flk-1) pTyr996.
Purification Affinity chromatography on Protein G
Alternative Name CD309 / VEGFR-2 / Flk-1 (KDR Antibody Abstract)
Background KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2
Molecular Weight 151527 Da
Gene ID 3791, 9606
UniProt P35968
Research Area Cytokines, Receptors
Application Notes ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody (2) anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody (Image 2)
Background publications Wittko, Schänzer, Kuzmichev et al.: "VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 27, pp. 8704-14, 2009 (PubMed).

Le Boeuf, Houle, Huot: "Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39175-85, 2004 (PubMed).

Lee, Bone, Strege et al.: "VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia." in: Blood, Vol. 104, Issue 3, pp. 788-94, 2004 (PubMed).

Validation Images
Catalog No. ABIN358131
357.50 $
Plus shipping costs $45.00
Quantity
Price
0.4 mL
357.50 $

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