Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody

Details for Product No. ABIN358131
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f ... show more
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f21.4, wu:fc31a09, fk52c05, flk, kdr, kdra, vegfr2, vegfr4, vegr2, wu:fk52c05 show less
Epitope
pTyr996
(60), (45), (38), (38), (28), (22), (16), (16), (15), (13), (10), (9), (8), (8), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(474), (290), (186), (64), (61), (53), (49), (26), (4), (2), (2), (2), (2), (2), (2), (2), (1)
Host
Rabbit
(438), (72), (35), (3), (2), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(33), (15), (12), (10), (9), (6), (6), (6), (6), (6), (6), (6), (6), (6), (3), (3), (3), (3), (2), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(375), (172), (168), (111), (85), (78), (60), (47), (31), (24), (10), (7), (7), (4), (3), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN358131
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y996 of human KDR/FLK1
Specificity This antibody detects CD309 (KDR/Flk-1) pTyr996.
Purification Affinity chromatography on Protein G
Alternative Name CD309 / VEGFR-2 / Flk-1
Background KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
Alternate names: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2
Molecular Weight 151527 Da
Gene ID 3791, 9606
UniProt P35968
Research Area Cytokines, Receptors
Application Notes ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody (2) anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (pTyr996) antibody (Image 2)
Background publications Lee, Bone, Strege et al.: "VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia." in: Blood, Vol. 104, Issue 3, pp. 788-94, 2004 (PubMed).

Le Boeuf, Houle, Huot: "Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39175-85, 2004 (PubMed).

Wittko, Schänzer, Kuzmichev et al.: "VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 27, pp. 8704-14, 2009 (PubMed).

Validation Images
Did you look for something else?
back to top