IGF1 antibody

Catalog No. ABIN360897

The Hamster Monoclonal anti-IGF1 antibody (Clone 2F54) (ABIN360897) specifically detects IGF1 in WB. The antibody is reactive with Mouse samples.

Quick Overview for IGF1 antibody (ABIN360897)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This IGF1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 2F54

Product Details anti-IGF1 Antibody

Specificity: This antibody detects IGF-1. No cross activity to other IGFBPs.

Purification: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IGF-1

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Alternative Name: Insulin-Like Growth Factor I / IGF1

Background: Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.Synonyms: IBP1, IGF-I, Somatomedin

Gene ID: 16000

NCBI Accession: NP_001104745

UniProt: P05017

Pathways: RTK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation