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ATF2 antibody (AA 67-71)
ATF2
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ATF2 Antibody
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Target
See all ATF2 Antibodies
ATF2
(Activating Transcription Factor 2 (ATF2))
Binding Specificity
All epitopes for ATF2 antibodies
AA 67-71
Reactivity
All reactivities for ATF2 antibodies
Human, Mouse, Rat
Host
All hosts for ATF2 antibodies
Rabbit
Clonality
All clonalities for ATF2 antibodies
Polyclonal
Conjugate
All conjugates for ATF2 antibodies
This ATF2 antibody is un-conjugated
Application
All applications for ATF2 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
The antibody detects endogenous level of total ATF2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 67-71 or 49-53 (D-Q-T-P-T) derived from Human ATF2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for ATF2
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Target
ATF2
(Activating Transcription Factor 2 (ATF2))
Alternative Name
ATF2 (ATF2 Products )
Synonyms
CRE-BP1 antibody, CREB2 antibody, HB16 antibody, TREB7 antibody, CG12850 antibody, CG3749 antibody, dATF-2 antibody, DmelCG30420 antibody, CG30420 antibody, CHN1 antibody, Atf-2 antibody, CRE-BP antibody, Creb2 antibody, D130078H02Rik antibody, D18875 antibody, Tg(Gzma-Klra1)7Wum antibody, mXBP antibody, atf2-A antibody, atf2l antibody, activating transcription factor 2 antibody, Activating transcription factor-2 antibody, activating transcription factor 2 S homeolog antibody, ATF2 antibody, Atf-2 antibody, Atf2 antibody, atf2.S antibody, atf2 antibody
Background
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
Molecular Weight
65-75 kDa
NCBI Accession
NP_001871
UniProt
P15336
Pathways
MAPK Signaling , RTK Signaling , Thyroid Hormone Synthesis , Activation of Innate immune Response , Chromatin Binding , Myometrial Relaxation and Contraction , Synaptic Membrane , Tube Formation , Toll-Like Receptors Cascades
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