JAK1 antibody (AA 1020-1024)
(1 reference)-
- Target See all JAK1 Antibodies
- JAK1 (Janus Kinase 1 (JAK1))
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Binding Specificity
- AA 1020-1024
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This JAK1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- The antibody detects endogenous level of total JAK1 protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Peptide sequence around AA 1020-1024 (K-E-Y-Y-T) derived from Human JAK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Isotype
- IgG
- Top Product
- Discover our top product JAK1 Primary Antibody
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anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1023) antibody
JAK1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (AA 120-380) antibodyJAK1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (pTyr1022) antibodyJAK1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (AA 960-1040) antibodyJAK1 Reactivity: Human IHC, ELISA Host: Mouse Monoclonal unconjugated
anti-Janus Kinase 1 (JAK1) (AA 1020-1024) antibodyJAK1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (Ser639) antibodyJAK1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 Reactivity: Human, Rat WB, IP Host: Mouse Monoclonal 7B1-B6-G7 unconjugated
anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibodyJAK1 Reactivity: Human WB Host: Rabbit Polyclonal RB43809 unconjugated
anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibodyJAK1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB43812 unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 Reactivity: Human, Mouse, Rat IHC (p) Host: Mouse Monoclonal 7G6 unconjugated
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- Application Notes
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).
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: "Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).
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- Target
- JAK1 (Janus Kinase 1 (JAK1))
- Alternative Name
- JAK1 (JAK1 Products)
- Synonyms
- JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
- Background
- Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
- Molecular Weight
- 130 kDa
- NCBI Accession
- NP_002218
- UniProt
- P23458
- Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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