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ERBB3 antibody (AA 1287-1291)

ERBB3 Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN363078
  • Target See all ERBB3 Antibodies
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    Binding Specificity
    • 28
    • 26
    • 21
    • 15
    • 15
    • 12
    • 9
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1287-1291
    Reactivity
    • 178
    • 126
    • 111
    • 17
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 184
    • 28
    • 1
    • 1
    Rabbit
    Clonality
    • 183
    • 31
    Polyclonal
    Conjugate
    • 109
    • 13
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This ERBB3 antibody is un-conjugated
    Application
    • 99
    • 67
    • 53
    • 53
    • 50
    • 30
    • 26
    • 20
    • 18
    • 16
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    Specificity
    The antibody detects endogenous level of total Her3/ErbB3 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around AA 1287-1291 (Q-G-Y-E-E) derived from Human Her3, ErbB3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotype
    IgG
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  • Application Notes
    Immunofluorescence: 1:100-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    Alternative Name
    Her3/ErbB3 (ERBB3 Products)
    Synonyms
    ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
    Background
    Binds and is activated by neuregulins and NTAK.
    Molecular Weight
    185 kDa
    NCBI Accession
    NP_001005
    UniProt
    P21860
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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