EGLN1 antibody (AA 1-50)

Catalog No. ABIN363411

Product Details anti-EGLN1 Antibody

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGLN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Specificity: Reacts with human HPH-2

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Does not react in mouse. Not tested in other species

Purification: Antigen affinity purified

Immunogen: Synthetic peptide between residues 1 and 50 of human PHD2/HIF Prolyl Hydroxylase 2 using the numbering given in entry NP_071334.1 (GeneID 54583).

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
FC 1:10-1:1000, WB 1:500-1:2500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 Mg/M

Buffer: Tris-citrate/phosphate, pH 7-8, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

Target Details for EGLN1

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Alternative Name: Hypoxia-Inducible Factor Prolyl Hydroxylase 2 (EGLN1 Products)

Synonyms: EGLN1 antibody, egln2 antibody, phd2 antibody, zgc:92314 antibody, AI503754 antibody, C1orf12 antibody, HIF-PH2 antibody, HPH-2 antibody, Hif-p4h-2 antibody, ORF13 antibody, Phd2 antibody, SM-20 antibody, PHD-2 antibody, PHD2 antibody, ECYT3 antibody, HIFPH2 antibody, HPH2 antibody, SM20 antibody, ZMYND6 antibody, egl nine homolog 1 (C. elegans) antibody, egl-9 family hypoxia inducible factor 1 antibody, egl-9 family hypoxia-inducible factor 1 S homeolog antibody, egl-9 family hypoxia-inducible factor 1b antibody, egl-9 family hypoxia-inducible factor 1 antibody, EGLN1 antibody, egln1.S antibody, egln1b antibody, Egln1 antibody

Background: HIF-PH2, under normoxic conditions,catalizes the post-translational formation of 4-hydroxyproline on HIF-alpha leading to its proteasomal degradation. This antibody has been tested on human glioblastoma cell lysates.

Gene ID: 54583

Pathways: cAMP Metabolic Process, Warburg Effect