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SLC6A3 antibody (N-Term)

SLC6A3 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN372309
  • Target See all SLC6A3 Antibodies
    SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))
    Binding Specificity
    • 16
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 48
    • 38
    • 35
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 58
    • 4
    Polyclonal
    Conjugate
    • 37
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC6A3 antibody is un-conjugated
    Application
    • 50
    • 25
    • 21
    • 15
    • 13
    • 13
    • 11
    • 10
    • 7
    • 7
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes SLC6A3/DAT1 (N-term).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography.
    Immunogen
    Synthetic peptide corresponding to N-terminal residues of Human DAT (Sodium-dependent Dopamine Transporter).
    Isotype
    IgG
    Top Product
    Discover our top product SLC6A3 Primary Antibody
  • Application Notes
    Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL. ELISA: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody undiluted (in aliquots) at-20 °C.
  • Target
    SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))
    Alternative Name
    SLC6A3 / DAT (SLC6A3 Products)
    Synonyms
    DAT antibody, SLC6A3 antibody, Dat1 antibody, DAT1 antibody, PKDYS antibody, solute carrier family 6 member 3 antibody, solute carrier family 6 (neurotransmitter transporter), member 3 antibody, Sodium-dependent dopamine transporter antibody, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 antibody, SLC6A3 antibody, slc6a3 antibody, dat-1 antibody, Slc6a3 antibody
    Background
    Plasmalemmal neurotransmitter transporters sequester synaptic and peri synaptic transmitter into presynaptic elements. The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. Levels of DAT protein expression are altered by chronic drug administration. The activity of the DAT reuptake carrier is sodium dependent, and it is suspected to play a role in such neurologic and psychiatric disorders as Parkinson's disease, Tourette's disease, schizophrenia, and addiction. It is a 12 transmembrane domain transporter with the N and C terminal regions located within the cytoplasm.Synonyms: DA transporter, DAT1, Sodium-dependent dopamine transporter, Solute carrier family 6 member 3
    Molecular Weight
    68 kDa.
    Gene ID
    6531
    NCBI Accession
    NP_001035
    UniProt
    Q01959
    Pathways
    Dopaminergic Neurogenesis
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