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ACVR1 antibody (AA 475-509)

ACRV1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN372397
  • Target See all ACVR1 (ACRV1) Antibodies
    ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
    Binding Specificity
    • 17
    • 15
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 475-509
    Reactivity
    • 78
    • 39
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 75
    • 5
    • 2
    • 2
    Rabbit
    Clonality
    • 82
    • 2
    Polyclonal
    Conjugate
    • 44
    • 14
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACVR1 antibody is un-conjugated
    Application
    • 75
    • 49
    • 40
    • 11
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody recognizes Activin Receptor Type IA (ACVR1).
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Protein G Chromatography.
    Immunogen
    Synthetic peptide within amino acids 475-509 of human ACVR1.
    Isotype
    IgG
    Top Product
    Discover our top product ACRV1 Primary Antibody
  • Application Notes
    Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western blot: 3-5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month (in aliquots) at-20 °C for longer.
  • Target
    ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
    Abstract
    ACRV1 Products
    Synonyms
    ACTRI antibody, ACVR1A antibody, ACVRLK2 antibody, ALK2 antibody, FOP antibody, SKR1 antibody, TSRI antibody, ActR-IA antibody, ActR-I antibody, ActRIA antibody, Acvr antibody, Acvrlk2 antibody, Alk-2 antibody, Alk8 antibody, D330013D15Rik antibody, Tsk7L antibody, actri antibody, acvr1 antibody, acvr1-a antibody, acvr1-b antibody, acvr1a antibody, acvrlk2 antibody, alk-2 antibody, alk2 antibody, alk8 antibody, fop antibody, sax antibody, skr1 antibody, tsri antibody, xALK-2 antibody, activin A receptor type 1 antibody, activin A receptor, type 1 antibody, activin A receptor type 1 S homeolog antibody, ACVR1 antibody, Acvr1 antibody, acvr1.S antibody
    Background
    Activin Receptor Type IA on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Activin receptor IA is highly conserved and is a receptor for BMP2 and BMP4.Synonyms: ACRV1A, ACVRLK2, ALK2, Activin receptor type IA, Activin receptor-like kinase 2, SKR1, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I
    Molecular Weight
    57 kDa.
    Gene ID
    90
    NCBI Accession
    NP_001096
    UniProt
    Q04771
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