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GRIA2 antibody
GRIA2
Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Chicken, Non-Human Primate
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GRIA2 Antibody
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Target
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GRIA2
(Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
Reactivity
All reactivities for GRIA2 antibodies
Human, Rat, Mouse, Zebrafish (Danio rerio), Chicken, Non-Human Primate
Host
All hosts for GRIA2 antibodies
Rabbit
Clonality
All clonalities for GRIA2 antibodies
Polyclonal
Conjugate
All conjugates for GRIA2 antibodies
This GRIA2 antibody is un-conjugated
Application
All applications for GRIA2 antibodies
Western Blotting (WB)
Specificity
This antibody is specific for the ~100k GluR2 protein.
Cross-Reactivity (Details)
Species reactivity (expected):Chicken, Human, Mouse, Zebrafish and non-Human Primates. Species reactivity (tested):Rat.
Purification
Affinity Chromatography.
Immunogen
Peptide corresponding to amino acid residues from rat GluR2, conjugated to keyhole limpet hemocyanin (KLH).
Isotype
IgG
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Discover our top product GRIA2 Primary Antibody
Alternatives
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anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibody
GRIA2
Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Western blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at-20 °C.
Target Details for GRIA2
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Target
GRIA2
(Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
Alternative Name
Glutamate Receptor 2 / GLUR2 (GRIA2 Products )
Synonyms
GLUR2 antibody, GLURB antibody, GluA2 antibody, GluR-K2 antibody, HBGR2 antibody, GluR-2 antibody, GluR-B antibody, Glur-2 antibody, Glur2 antibody, GluR2 antibody, gluR-B antibody, glur2a antibody, gria2.1 antibody, zfGRIA2[a] antibody, glur2 antibody, glutamate ionotropic receptor AMPA type subunit 2 antibody, glutamate receptor, ionotropic, AMPA 2 antibody, glutamate receptor, ionotropic, AMPA2 (alpha 2) antibody, glutamate receptor, ionotropic, AMPA 2a antibody, glutamate receptor, ionotropic, AMPA 2 S homeolog antibody, GRIA2 antibody, Gria2 antibody, gria2a antibody, gria2.S antibody
Background
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003)Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic
Gene ID
29627
NCBI Accession
NP_001077280
UniProt
P19491
Pathways
PI3K-Akt Signaling
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