You are viewing an incomplete version of our website. Please click to reload the website as full version.

anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibody

Details for Product No. ABIN374464, Supplier: Login to see
Antigen
  • ANTXR1
  • ATR
  • TEM8
  • 2310008J16Rik
  • 2810405N18Rik
  • Antrx1
  • Tem8
Epitope
C-Term
24
24
14
12
6
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
137
44
39
2
1
1
1
1
1
Host
Goat
122
17
5
Clonality
Polyclonal
Conjugate
Un-conjugated
9
9
9
8
7
7
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
77
77
36
24
20
13
5
2
2
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen Peptide with sequence C-RAPPPSRPPPRPSV, from the C Terminus of the protein sequence
Specificity This antibody reacts to Anthrax toxin receptor 1.
Cross-Reactivity (Details) Species reactivity (expected):Rat, Bovine, Canine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name Anthrax Toxin Receptor 1 (ANTXR1 Antibody Abstract)
Background TEM8 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has also been shown to be a docking protein or receptor for Bacillus anthracistoxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor(EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
Gene ID 84168, 9606
UniProt Q9H6X2
Research Area Toxicology, Receptors
Pathways
Application Notes Peptide ELISA: 1/64000. Western blot: 0.2 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibody (ABIN374464) anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibody
Background publications Carson-Walter, Watkins, Nanda et al.: "Cell surface tumor endothelial markers are conserved in mice and humans." in: Cancer research, Vol. 61, Issue 18, pp. 6649-55, 2001 (PubMed).

Cross, Lindsey, Fantes et al.: "The structure of a subterminal repeated sequence present on many human chromosomes." in: Nucleic acids research, Vol. 18, Issue 22, pp. 6649-57, 1991 (PubMed).