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PDX1 antibody (C-Term)
PDX1
Reactivity: Human, Mouse, Rat, Chimpanzee
WB, IHC (p)
Host: Goat
Polyclonal
unconjugated
Product Details anti-PDX1 Antibody
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Target
See all PDX1 Antibodies
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
Binding Specificity
All epitopes for PDX1 antibodies
C-Term
Reactivity
All reactivities for PDX1 antibodies
Human, Mouse, Rat, Chimpanzee
Host
All hosts for PDX1 antibodies
Goat
Clonality
All clonalities for PDX1 antibodies
Polyclonal
Conjugate
All conjugates for PDX1 antibodies
This PDX1 antibody is un-conjugated
Application
All applications for PDX1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody reacts to Insulin promoter factor 1.
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, Rat, Canine. Species reactivity (tested):Human.
Purification
Affinity chromatography
Immunogen
Peptide with sequence C-KSFKANLENPIRLA, from the C Terminus of the protein sequence
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Alternatives
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Application Details
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Application Notes
Peptide ELISA: 1/32000. Western Blot: 0.1 - 1 μg/mL. Immunohistochemistry on paraffin sections: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PDX1
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Target
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
Alternative Name
Insulin Promoter Factor 1 (PDX1 Products )
Synonyms
GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
Background
PDX1 (Pancrease/duodenum homeobox 1, Insulin promoter factor 1, IPF1, Islet/duodenum homeobox 1, IDX1, Somatatostatin transactivating factor 1, STF1, Insulin upstream factor 1, UUF1, Glucose-sensitive factor, GSF) activates transcription of the insulin and somatostain genes. PDX1 is required for maintaining the hormone-producing phenotype of the beta-cell.Synonyms: GSF, Glucose-sensitive factor, IDX-1, IPF-1, IPF1, IUF-1, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, PDX-1, PDX1, Pancreas/duodenum homeobox protein 1, STF-1, Somatostatin-transactivating factor 1
Gene ID
3651
NCBI Accession
NP_000200
UniProt
P52945
Pathways
Nuclear Receptor Transcription Pathway , Positive Regulation of Peptide Hormone Secretion , Steroid Hormone Mediated Signaling Pathway , Hormone Transport , Carbohydrate Homeostasis , Chromatin Binding , Maintenance of Protein Location
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