You are viewing an incomplete version of our website. Please click to reload the website as full version.

Melanoma Gp100 (C-Term) antibody

Details for Product No. ABIN374704, Supplier: Log in to see
Antigen
  • silverb
Epitope
C-Term
7
3
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
14
Host
Goat
7
4
3
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Western Blotting (WB)
8
8
4
3
2
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen Peptide with sequence CPIGENSPLLSGQQ, from the C Terminus of the protein sequence according to NP_008859.1
Specificity This antibody recognizes Silver homologue / Pmel17.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography
Background Melanoma gp100, a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes. It is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.Synonyms: D12S53E, ME20-M, Melanocyte lineage-specific antigen GP100, Melanocyte protein Pmel 17, Melanoma-associated ME20 antigen, PMEL17, SILV, Silver locus protein homolog
Molecular Weight 70.3kDa (NP_008859.1).
Gene ID 6490
NCBI Accession NP_001186982
UniProt P40967
Research Area Cancer, Metabolism
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Melanoma Gp100 (C-Term) antibody (ABIN374704) anti-Melanoma Gp100 (C-Term) antibody
 image for anti-Melanoma Gp100 (C-Term) antibody (ABIN374704) anti-Melanoma Gp100 (C-Term) antibody (Image 2)
Background publications Fowler, Koulov, Alory-Jost, Marks, Balch, Kelly: "Functional amyloid formation within mammalian tissue." in: PLoS biology, Vol. 4, Issue 1, pp. e6, 2006 (PubMed).