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SUMO3 antibody (SMT3 Suppressor of Mif Two 3 Homolog 3 (S. Cerevisiae))

Details for Product anti-SUMO3 Antibody No. ABIN387787, Supplier: Log in to see
Antigen
  • 2810014B19Rik
  • AA409334
  • ATSUMO3
  • AW121497
  • AW536077
  • D10Ertd345e
  • fa94a11
  • fc66f10
  • fl11h12
  • HSMT3
  • im:7141764
  • MCO15.12
  • MCO15_12
  • SMALL UBIQUITIN-LIKE MODIFIER 3
  • small ubiquitin-like modifier 3
  • smt3a
  • SMT3A
  • Smt3A
  • Smt3B
  • SMT3B
  • Smt3h1
  • SMT3H1
  • smt3h1
  • SMT3H2
  • SUM3
  • SUMO-3
  • sumo2
  • sumo3
  • SUMO 3
  • SUMO3
  • sumo3l
  • wu:fa94a11
  • wu:fb55d09
  • wu:fc66f10
  • wu:fl11h12
  • zgc:65847
  • zgc:85643
  • zgc:86902
Reactivity
Human
80
20
13
2
2
2
2
2
2
2
1
1
Host
Mouse
57
21
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This SUMO3 antibody is un-conjugated
3
3
3
3
3
3
Application
Western Blotting (WB)
80
49
31
14
5
5
3
1
1
Supplier
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Immunogen Purified recombinant GST-SUMO3 fusion protein was used as immunogen.
Clone 76AT630-91-31
Isotype IgG1
Specificity Purified recombinant GST-SUMO3 fusion protein was used as immunogen.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name SUMO3 (SUMO3 Antibody Abstract)
Background SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).
Synonyms: Small ubiquitin-related modifier 3, SUMO-3, Ubiquitin-like protein SMT3A, SMT3 homolog 1, SUMO-2, SMT3A, SMT3H1
Molecular Weight 11637 DA
Gene ID 6612
UniProt P55854
Research Area Apoptosis/Necrosis, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-SUMO3 antibody (SMT3 Suppressor of Mif Two 3 Homolog 3 (S. Cerevisiae)) (ABIN387787) The anti-SUMO3 monoclonal antibody (ABIN387787) is used in Western blot to detect GST...
Product cited in: Wu, Kong, Ji, Zeng, Potts, Yokomori, Yu: "Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl." in: Genes & development, Vol. 26, Issue 13, pp. 1473-85, 2012 (PubMed).

Background publications Han, Huang, Sun, Xiang, Wang, Yeh, Chen, Li, Shi, Cang, Sun, Wang, Wang, Gao, Yi: "SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 12906-15, 2010 (PubMed).

Couch, Wang, Bamlet, de Andrade, Petersen, McWilliams: "Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 251-7, 2010 (PubMed).

Uwada, Tanaka, Yamaguchi, Uchimura, Shibahara, Nakao, Saitoh: "The p150 subunit of CAF-1 causes association of SUMO2/3 with the DNA replication foci." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 407-13, 2010 (PubMed).

Hofmann, Arduini, Nicol, Camacho, Lessard, Fuller-Pace, de Lanerolle: "SUMOylation of nuclear actin." in: The Journal of cell biology, Vol. 186, Issue 2, pp. 193-200, 2009 (PubMed).

Brunet Simioni, De Thonel, Hammann, Joly, Bossis, Fourmaux, Bouchot, Landry, Piechaczyk, Garrido: "Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity." in: Oncogene, Vol. 28, Issue 37, pp. 3332-44, 2009 (PubMed).