Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term), (AA 27-55) antibody

Details for Product No. ABIN388572
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Antigen
Synonyms 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, Nyw1, DCAF3, WDR94
Epitope
N-Term, AA 27-55
(18), (11), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(52), (46), (30), (13), (12), (1)
Host
Rabbit
(59), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(51), (26), (26), (14), (10), (7), (4), (3), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN388572
291.50 $
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Immunogen This AMBRA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 AA from the N-terminal region of human AMBRA1.
Clone RB13139
Isotype Ig
Specificity This AMBRA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AMBRA1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AMBRA1
Background AMBRA1 regulates autophagy and development of the nervous system. This protein is involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
Synonyms: Activating molecule in BECN1-regulated autophagy protein 1, KIAA1736
Molecular Weight 142507 DA
Gene ID 55626
UniProt Q9C0C7
Research Area Autophagy, Cell Cycle, Neurology, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term), (AA 27-55) antibody Western blot analysis of AMBRA1 Antibody (N-term) in HepG2 cell line lysates (35 µg/lane). AMBRA1(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
anti-Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term), (AA 27-55) antibody (2) Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with AMBRA1 antibody (N-term) (ABIN388572), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

Validation Images
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