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MAP2 antibody (MAP-2) (AA 1766-1796)

Details for Product anti-MAP-2 Antibody No. ABIN388759, Supplier: Log in to see
Antigen
  • a730034c02
  • MAP-2
  • MAP2A
  • MAP2B
  • MAP2C
  • MAP2R
  • MGC53131
  • Mtap-2
  • Mtap2
  • p67
  • p67eIF2
  • xmap2
Epitope
AA 1766-1796, C-Term
24
21
13
13
12
8
5
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
291
180
149
122
27
20
16
14
8
5
3
1
1
Host
Rabbit
173
169
18
4
Clonality (Clone)
Polyclonal ()
Conjugate
This MAP2 antibody is un-conjugated
17
16
12
12
8
8
6
5
4
4
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
270
137
119
105
96
66
50
29
23
22
14
13
11
4
3
3
2
1
Supplier
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Immunogen This MAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1766-1796 AA from the C-terminal region of human MAP2.
Clone RB02868
Isotype Ig
Specificity This MAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418~447 amino acids from the C-terminal region of human MAP2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAP2
Background This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The exact function of this gene is still unknown. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development.
Synonyms: Microtubule-associated protein 2, MAP-2, MAP2
Molecular Weight 199610 DA
Gene ID 4133
UniProt P11137
Research Area Stem Cells, Signaling, Neurology, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MAP2 antibody (MAP-2) (AA 1766-1796) (ABIN388759) Western blot analysis of hMAP2-Q425 (arrow) using rabbit polyclonal hMAP2-Q425 Antibo...
Immunohistochemistry (IHC) image for anti-MAP2 antibody (MAP-2) (AA 1766-1796) (ABIN388759) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with hMAP2-Q...
Background publications Liu, Saad, Shen, Silverman: "Diagnostic value of microtubule-associated protein-2 (MAP-2) for neuroendocrine neoplasms." in: Advances in anatomic pathology, Vol. 10, Issue 2, pp. 101-6, 2003 (PubMed).

DeTure, Di Noto, Purich: "In vitro assembly of Alzheimer-like filaments. How a small cluster of charged residues in Tau and MAP2 controls filament morphology." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 34755-9, 2002 (PubMed).

Al-Bassam, Ozer, Safer, Halpain, Milligan: "MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments." in: The Journal of cell biology, Vol. 157, Issue 7, pp. 1187-96, 2002 (PubMed).