The Rabbit Polyclonal anti-TDGF1 antibody (Clone RB3957) (ABIN388791) specifically detects TDGF1 in WB and IHC (p).
The antibody is reactive with Human samples.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CRIPTO (TDGF1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human CRIPTO (TDGF1).
TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. This protein could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. It is preferentially expressed in gastric and colorectal carcinomas compared to their normal counterparts.