TDGF1 antibody (AA 21-70)
Quick Overview for TDGF1 antibody (AA 21-70) (ABIN7231746)
Target
See all TDGF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 21-70
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Purpose
- Rabbit Anti-TDGF1 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of TDGF1 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human TDGF1 protein at AA range: 21-70
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))
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Alternative Name
- TDGF1
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Background
- Teratocarcinoma-derived growth factor 1, Cripto-1 growth factor, CRGF, Epidermal growth factor-like cripto protein CR1TDGF1 encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in TDGF1 are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.
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Molecular Weight
- 20kD
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Gene ID
- 6997
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UniProt
- P13385
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Pathways
- EGFR Signaling Pathway
Target
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