Did you know that you can buy products from over 140 different suppliers from us?

Indoleamine 2,3-Dioxygenase 1 (IDO1) (C-Term), (AA 374-403) antibody

Details for Product No. ABIN389194
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Epitope
C-Term, AA 374-403
(9), (7), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(79), (33), (18), (17), (12), (12)
Host
Rabbit
(50), (34), (6), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(73), (42), (19), (17), (11), (10), (8), (5), (4), (4), (3)
Pubmed 2 references available
Quantity 400 µL
Options
Shipping to United States (Change)
Availability Discontinued
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN389194
291.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This INDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 AA from the C-terminal region of human INDO.
Clone RB15061
Isotype Ig
Specificity This INDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374~403 amino acids from the C-terminal region of human INDO.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name INDO
Background Gamma-interferon (IFNG, MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO, EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM]
Synonyms: Indoleamine 2,3-dioxygenase, IDO, EC 1.13.11.52, Indoleamine-pyrrole 2,3-dioxygenase, INDO, IDO
Molecular Weight 45326 DA
Gene ID 3620
UniProt P14902
Research Area Stem Cells, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (C-Term), (AA 374-403) antibody Western blot analysis of anti-INDO Antibody (C-term) (ABIN389194) in 293 cell line lysates (35 µg/lane). INDO(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (C-Term), (AA 374-403) antibody (2) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with INDO antibody (C-term) (ABIN389194), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Scheler, Wenzel, Tüting et al.: "Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation?" in: The American journal of pathology, Vol. 171, Issue 6, pp. 1936-43, 2007 (PubMed).

Maghzal, Thomas, Hunt et al.: "Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells." in: The Journal of biological chemistry, Vol. 283, Issue 18, pp. 12014-25, 2008 (PubMed).

Validation Images
back to top