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TRF1 antibody (Telomeric Repeat Binding Factor (NIMA-Interacting) 1) (AA 337-366)

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Antigen
Synonyms
wu:fb74c04, TERF1, ERF1, DKFZp459A0713, AGR, AGR1, AGRAVITROPIC ROOT, AGRAVITROPIC ROOT 1, ARABIDOPSIS THALIANA PIN-FORMED 2, ATPIN2, AUXIN TRANSPORT PROTEIN EIR1, ETHYLENE INSENSITIVE ROOT 1, MUL3.3, ... show more
wu:fb74c04, TERF1, ERF1, DKFZp459A0713, AGR, AGR1, AGRAVITROPIC ROOT, AGRAVITROPIC ROOT 1, ARABIDOPSIS THALIANA PIN-FORMED 2, ATPIN2, AUXIN TRANSPORT PROTEIN EIR1, ETHYLENE INSENSITIVE ROOT 1, MUL3.3, MUL3_3, PIN-FORMED 2, PIN2, POLAR-AUXIN-TRANSPORT EFFLUX COMPONENT AGRAVITROPIC 1, WAV6, WAVY ROOTS 6, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1, Pin2, Trbf1, Trf1 show less
Alternatives
Epitope
AA 337-366, C-Term
(23), (8), (6), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(113), (29), (18), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(74), (23), (18)
Clonality (Clone)
Polyclonal ()
Conjugate
This TRF1 antibody is un-conjugated
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(84), (63), (18), (13), (12), (11), (9), (8), (2), (1), (1)
Pubmed 2 references available
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Quantity 400 μL
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Immunogen This TRF (TERF1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 AA from the C-terminal region of human TRF (TERF1).
Clone RB15106
Isotype Ig
Specificity This TRF (TERF1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344~374 amino acids from the C-terminal region of human TERF1.
Predicted Reactivity Hamster
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name TRF (TERF1) (TERF1 Antibody Abstract)
Background TERF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus.
Synonyms: Telomeric repeat binding factor (NIMA-interacting) 1, TERF1
Molecular Weight 50246 DA
Gene ID 7013
UniProt P54274
Research Area Stem Cells, Signaling, Chromatin, Cell Structure
Pathways Cell Division Cycle, Telomere Maintenance
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-TRF1 antibody (Telomeric Repeat Binding Factor (NIMA-Interacting) 1) (AA 337-366) (ABIN389240) Western blot analysis of anti-TERF1(C-term) Pab (ABIN389240) in Jurkat cell line lysa...
Background publications Kim, Kang, Nam et al.: "Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation." in: The Journal of biological chemistry, Vol. 283, Issue 20, pp. 14144-52, 2008 (PubMed).

Etheridge, Compton, Barrientos et al.: "Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation." in: The Journal of biological chemistry, Vol. 283, Issue 11, pp. 6935-41, 2008 (PubMed).

Catalog No. ABIN389240
$324.50
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