AASS antibody (AA 264-294)

Catalog No. ABIN389270

Product Details anti-AASS Antibody

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Binding Specificity: AA 264-294

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AASS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-294 amino acids from the Central region of human AASS.

Clone: RB14893

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for AASS

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Alternative Name: AASS (AASS Products)

Synonyms: LKR/SDH antibody, LKRSDH antibody, LORSDH antibody, LKR antibody, LOR antibody, LOR/SDH antibody, Lorsdh antibody, SDH antibody, aminoadipate-semialdehyde synthase antibody, AASS antibody, Aass antibody

Background: AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.

Molecular Weight: 102132

Gene ID: 10157

NCBI Accession: NP_005754

UniProt: Q9UDR5

Pathways: SARS-CoV-2 Protein Interactome