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Details for Product No. ABIN391303

Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (C-Term), (AA 479-510) antibody

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Antigen
Synonyms AMPK, AMPK1, AMPKa1, AMPKalpha1, AI194361, AI450832, AL024255, C130083N04Rik, ampk, ampka1, cb116, sb:cb130, im:7154392, wu:fa94c10, Prkaa1, PRKAA1
Epitope
»Alternatives C-Term, AA 479-510
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN391303
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This AMPK alpha 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-510 AA from the C-terminal region of human AMPK alpha 1.
Clone RB2520
Isotype Ig
Specificity This AMPK alpha 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487~517 amino acids from the C-terminal region of human AMPK alpha 1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AMPK alpha 1
Background AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.
Synonyms: 5'-AMP-activated protein kinase, catalytic alpha-1 chain, AMPK alpha-1 chain
Molecular Weight 62793 DA
Gene ID 5562
UniProt Q13131
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Zhang, Ye, Wu et al.: "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." in: Genome research, Vol. 10, Issue 10, pp. 1546-60, 2000 (PubMed).

Alternatives for antigen "Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1)", type "Antibodies"
Hosts (171), (24)
Reactivities (173), (124), (117), (33), (28), (28), (28), (3), (3), (1), (1), (1)
Applications (132), (63), (50), (44), (40), (20), (19), (9), (8), (7), (3), (2), (1), (1), (1)
Conjugates (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1)
Epitopes (22), (20), (16), (15), (13), (12), (10), (7), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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