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EPH Receptor B2 antibody (N-Term)

EPHB2 Reactivity: Human, Mouse IHC (p) Host: Rabbit Polyclonal RB01650 unconjugated
Catalog No. ABIN391919
  • Target See all EPH Receptor B2 (EPHB2) Antibodies
    EPH Receptor B2 (EPHB2)
    Binding Specificity
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 103-133, N-Term
    Reactivity
    • 58
    • 28
    • 13
    • 3
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 43
    • 15
    • 5
    • 2
    Rabbit
    Clonality
    • 45
    • 20
    Polyclonal
    Conjugate
    • 36
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPH Receptor B2 antibody is un-conjugated
    Application
    • 46
    • 43
    • 25
    • 14
    • 11
    • 9
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This EphB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-133 amino acids from the N-terminal region of human EphB2.
    Clone
    RB01650
    Isotype
    IgG
    Top Product
    Discover our top product EPHB2 Primary Antibody
  • Application Notes
    IHC-P: 1:50~100. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Expiry Date
    6 months
  • Xue, Huang, Wang, Dong, Zhou: "EphrinB2 and EphB4 expression in pterygia: new insights and preliminary results." in: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, Vol. 44, Issue 2, pp. 185-8, (2009) (PubMed).

  • Target
    EPH Receptor B2 (EPHB2)
    Alternative Name
    EphB2 (EPHB2 Products)
    Synonyms
    CAPB antibody, DRT antibody, EK5 antibody, EPHT3 antibody, ERK antibody, Hek5 antibody, PCBC antibody, Tyro5 antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, RGD1564232 antibody, Cek5 antibody, Drt antibody, ETECK antibody, Erk antibody, Nuk antibody, Prkm5 antibody, Qek5 antibody, Sek3 antibody, cek5 antibody, ephb2 antibody, xEphB2 antibody, si:ch73-160e9.1 antibody, tpx2 antibody, wu:fb09e10 antibody, wu:fc64a03 antibody, wu:fi18g12 antibody, zgc:112296 antibody, EPH receptor B2 antibody, mitogen-activated protein kinase 1 antibody, Eph receptor B2 antibody, EPH receptor B2 L homeolog antibody, eph receptor B2a antibody, eph receptor B2b antibody, EPHB2 antibody, MAPK1 antibody, Ephb2 antibody, ephb2.L antibody, ephb2a antibody, ephb2b antibody
    Background
    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.
    Molecular Weight
    117493
    Gene ID
    2048
    NCBI Accession
    NP_004433, NP_059145
    UniProt
    P29323
    Pathways
    RTK Signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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