You are viewing an incomplete version of our website. Please click to reload the website as full version.

Activin A Receptor Type II-Like 1 (ACVRL1) (AA 474-503), (C-Term) antibody

Details for Product No. ABIN392242, Supplier: Login to see
Antigen
  • ACVRL1
  • vgb
  • alk1
  • zehn1109
  • hm:zehn1109
  • ACVRLK1
  • ALK-1
  • ALK1
  • HHT
  • HHT2
  • ORW2
  • SKR3
  • TSR-I
  • R-3
  • R3
  • SETHKIR
  • AI115505
  • AI427544
  • Acvrlk1
  • Alk1
Epitope
AA 474-503, C-Term
35
24
13
11
10
6
6
5
4
2
2
2
1
1
1
1
1
1
Reactivity
Human
127
35
27
3
2
2
Host
Rabbit
94
18
15
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
6
6
6
5
5
5
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
101
71
47
20
20
11
9
5
2
1
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 AA from the C-terminal region of human ACVRL1.
Clone RB03737
Isotype Ig
Specificity This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474~503 amino acids from the C-terminal region of human ACVRL1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ACVRL1 (ACVRL1 Antibody Abstract)
Background ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Synonyms: SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I
Molecular Weight 56124 DA
Gene ID 94
UniProt P37023
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Pathways
Application Notes WB = 1:1000, FACS = 1:10-50, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 474-503), (C-Term) antibody (ABIN392242) Western blot analysis of hACVRL1-L489 (ABIN392242) in Jurkat, HepG2 cell line lysates...
Immunohistochemistry (IHC) image for anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 474-503), (C-Term) antibody (ABIN392242) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Flow Cytometry (FACS) image for anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 474-503), (C-Term) antibody (ABIN392242) ACVRL1 Antibody (C-term) (ABIN392242) flow cytometry analysis of HepG2 cells (bottom ...
Background publications Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Attisano, Cárcamo, Ventura et al.: "Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors." in: Cell, Vol. 75, Issue 4, pp. 671-80, 1993 (PubMed).