This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This CYP21A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the N-terminal region of human CYP21A2.
CA21H antibody, CAH1 antibody, CPS1 antibody, CYP21 antibody, CYP21B antibody, P450c21B antibody, 21-OH antibody, 21OH antibody, 21OHA antibody, 21OHB antibody, CYP21OH-A antibody, Cyp21 antibody, Cyp21-ps1 antibody, Cyp21B antibody, Cyp21a2-ps antibody, Cyp21a2ps antibody, Oh21-1 antibody, Oh21-2 antibody, CYP21A antibody, 21-OHase antibody, cytochrome P450 family 21 subfamily A member 2 antibody, cytochrome P450, family 21, subfamily a, polypeptide 1 antibody, cytochrome P450c21 antibody, cytochrome P450, family 21, subfamily A, polypepide 2 antibody, cytochrome P450, family 21, subfamily A, polypeptide 2 antibody, steroid 21-hydroxylase-like antibody, CYP21A2 antibody, Cyp21a1 antibody, LOC101094596 antibody
Background
CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in CYP21A2 gene cause congenital adrenal hyperplasia.