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Details for Product No. ABIN392389

Aurora Kinase A (AURKA) (N-Term), (AA 90-120) antibody

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Antigen
Synonyms
AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6, ARK-1, Eg2, aik, ark1, aur-a, aura, aurka-a, aurora2, btak, stk15, stk6, s ... show more
Epitope
»Alternatives N-Term, AA 90-120
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN392389
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This AIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 AA from the N-terminal region of human AIK.
Clone RB00883
Isotype Ig
Specificity This AIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AIK.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AIK
Background Aurora A (AIK) plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Synonyms: Aurora/IPL1-related kinase 1, STK6, Aurora-A
Molecular Weight 46000 DA
Gene ID 6790
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Kimura, Kotani, Hattori et al.: "Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13766-71, 1997 (PubMed).

Alternatives for antigen "Aurora Kinase A (AURKA)", type "Antibodies"
Hosts (118), (43), (14), (2)
Reactivities (166), (58), (49), (26), (24), (14), (10), (1), (1), (1)
Applications (131), (62), (46), (43), (34), (29), (20), (17), (7), (4), (4), (1)
Conjugates (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Epitopes (29), (14), (12), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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