JAG2 antibody (AA 111-128)

Catalog No. ABIN401290

Product Details anti-JAG2 Antibody

Target: JAG2 (Jagged 2 (JAG2))

Binding Specificity: AA 111-128

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide corresponding to amino acids 111-128 of Mouse Jagged-2

Isotype: IgG

Application Details

Application Notes: ELISA: 1/20000 - 1/90000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.9 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Alternative Name: Jagged-2 / JAG2 (JAG2 Products)

Synonyms: D12Ggc2e antibody, Serh antibody, mJagged2-1 antibody, sm antibody, HJ2 antibody, SER2 antibody, jag2 antibody, serB antibody, zgc:152855 antibody, jagged 2 antibody, jagged 2b antibody, JAG2 antibody, jag2 antibody, Jag2 antibody, jag2b antibody

Background: Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.Synonyms: hJ2

Gene ID: 10090

UniProt: Q9QYE5

Pathways: Notch Signaling, Sensory Perception of Sound