HLAG antibody

Catalog No. ABIN2878447

The Mouse Monoclonal anti-HLAG antibody is suitable to detect HLAG in samples from Human. It has been validated for ELISA, FACS, IHC and IHC (fro).

Quick Overview for HLAG antibody (ABIN2878447)

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLAG antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: MEM-G-9

Product Details anti-HLAG Antibody

Specificity: Specifically recognises surface expressed native HLA-G1, when associated with beta 2 microglobulin, but not does recognise the isoforms HLA-G2, G3 and G4. Also reported to recognize the soluble isoform HLA-G5.

Purification: Protein A purified

Immunogen: Recombinant human HLA-G refolded with beta2 microglobulin.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo, IHC, IHC-Fr

Usage: Suitable for use in ELISA, Immunohistochemistry, Flow Cytometry. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1 x10⁶ in 100 μL. Immunohistochemistry: Frozen tissue only.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for HLAG

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Alternative Name: HLA-G

Background: Name/Gene ID: HLA-G

Synonyms: HLA-G, HLAG, HLA-6.0, MHC class I antigen G, HLA G antigen

Gene ID: 3135

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response