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HLAG antibody (AA 62-89)

HLAG Reactivity: Human WB, ELISA, FACS, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031240
  • Target See all HLAG Antibodies
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    Binding Specificity
    • 18
    • 15
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 62-89
    Reactivity
    • 120
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 64
    • 62
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 68
    • 63
    Polyclonal
    Conjugate
    • 49
    • 20
    • 19
    • 14
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLAG antibody is un-conjugated
    Application
    • 84
    • 66
    • 58
    • 42
    • 30
    • 27
    • 15
    • 13
    • 13
    • 11
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 62-89 from the human protein was used as the immunogen for this HLA-G antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HLAG Primary Antibody
  • Application Notes
    Titration of the HLA-G antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the HLA-G antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    Alternative Name
    HLA-G (HLAG Products)
    Synonyms
    MHC-G antibody, B-F antibody, B-F-S04 antibody, B-F-S05 antibody, B-F-S06 antibody, B-F-S07 antibody, B-FI antibody, B-FIV antibody, BF2 antibody, BFa2 antibody, BFw-03 antibody, BFw-05 antibody, BFz-01 antibody, major histocompatibility complex, class I, G antibody, MHC BF1 class I antibody, HLA-G antibody, BF1 antibody
    Background
    HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
    UniProt
    P17693
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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