DDR1 antibody (pTyr513)

Catalog No. ABIN482717

The Rabbit Polyclonal anti-DDR1 antibody is suitable to detect DDR1 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for DDR1 antibody (pTyr513) (ABIN482717)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DDR1 Antibody

Binding Specificity: AA 479-528, pTyr513

Specificity:

DDR1 (Phospho-Tyr513) Antibody detects endogenous levels of DDR1 only when phosphorylated at Tyr513.

PhosphorylationH:Y513 M:Y511 R:Y510

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DDR1 around the phosphorylation site of Tyr513.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.631988 (NCBI Gene Symbol: DDR1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Alternative Name: DDR1

Background:

Synonyms: CAK, CD167a antigen, Cell adhesion kinase, Discoidin receptor tyrosine kinase, EDDR1, Epithelial discoidin domain receptor 1 precursor, HGK2, Protein-tyrosine kinase RTK 6, RTK6, TRK E, TRKE, Tyrosine kinase DDR, Tyrosine- protein kinase CAK

NCBI Gene Symbol: DDR1

Molecular Weight: 101 kDa

Gene ID: 780

OMIM: 600408

UniProt: Q08345

Pathways: RTK Signaling, Smooth Muscle Cell Migration