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Homeobox C11 (HOXC11) (Middle Region) antibody

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Antigen
Synonyms HOXC11, HOX3H, Hox-3.7, RGD1305450
Epitope
Middle Region
(17), (16), (8), (3), (2), (2), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Rat (Rattus)
(51), (17), (3), (1), (1)
Host
Rabbit
(30), (28), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(54), (24), (21), (16), (10), (4), (3)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human HOXC11
Blocking Peptide Blocking peptide for this product available: ABIN978188
Sequence EAPPASGLAS RAEAGAEAEA EEENTNPSSS GSAHSVAKEP AKGAAPNAPR
Predicted Reactivity Bovine : 100 %, Mouse : 100 %, Rat : 100 %, Rabbit : 90 %, Dog : 80 %
Characteristics This is a rabbit polyclonal antibody against HOXC11. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HOXC11 (HOXC11 Antibody Abstract)
Background HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.
Molecular Weight 34 kDa
Gene ID 3227
NCBI Accession NM_014212, NP_055027
UniProt O43248
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 304 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Homeobox C11 (HOXC11) (Middle Region) antibody (ABIN486885) WB Suggested Anti-HOXC11 Antibody Titration: 0.2-1 ug/ml
Positive Contro...
Background publications Zhang, Hamada, Nishimoto et al.: "HOXC6 and HOXC11 increase transcription of S100beta gene in BrdU-induced in vitro differentiation of GOTO neuroblastoma cells into Schwannian cells." in: Journal of cellular and molecular medicine, Vol. 11, Issue 2, pp. 299-306, 2007 (PubMed).

Catalog No. ABIN486885
$289.00
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